Medicine

Progressing ASO therapies from advancement to execution

.Contending passions.R.S., M.S., H.G. as well as A.A.R. are planners of the 1M1M campaign. H.G. as well as A.A.R. are actually board of directors members as well as R.S., M.S. and A.A.R. are actually members of the medical advising board of N1C. A.A.R. reveals employment by LUMC, which possesses licenses on exon-skipping technology, a number of which has actually been licensed to BioMarin and also consequently sublicensed to Sarepta. As co-inventor of a few of these licenses, A.A.R. was entitled to a reveal of aristocracies. A.A.R. additionally discloses acting as impromptu consultant for PTC Rehabs, Sarepta Therapies, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Over the last 5 years, A.A.R. likewise carried out ad hoc consulting with for Alpha Anomeric. A.A.R. also reports subscription of the scientific advisory boards of Eisai, Hybridize Therapies, Muteness Therapeutics, Sarepta Therapeutics, Sapreme and also Mitorx. Over the last 5 years, A.A.R. was additionally a clinical advisory board member for ProQR. Wage for A.A.R. u00e2 s consulting and also suggesting activities is paid out to LUMC. Over the last 5 years, LUMC additionally obtained audio speaker gratuity coming from PTC Rehabs, Alnylam Netherlands, Italfarmaco and also Pfizer and also cashing for deal study coming from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Project backing is obtained coming from Sarepta Therapies and also Entrada by means of unlimited gives. H.G. has nothing to divulge relative to the subject matters covered within this composition. Before 5 years, he has actually also gotten consultancy gratuity coming from UCB. M.S. obtained working as a consultant gratuity coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa previously 5 years, all unrelated to today manuscript. R.S. possesses nothing at all to reveal in regard to the topics dealt with in this document. She has acquired speaker and/or consultancy gratuity or financing payments from Abbvie, Bial, STADA and also Everpharma before 5 years.

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